A trouble-maker from birth, her parents abandoned her at the age of 7. She was sent to live in an orphanage and was adopted by a family in rural Alabama. After 9 long years spent doing hard labor on their dairy farm, Nina realized that she was only adopted so that she could be slave labor for this worthless family. Deeply angered, she reacted the only way she knew how: she sought vengeance. Carefully, she plotted out the events of the "freak accident" that would be the untimely end to this family, and also allow her to fake her own death. On the chosen night, a silo full of grain collapsed and crushed the farm house, killing all inside. The only remaining family member was the farmer's oldest daughter Lenore, who was on her way to West Point Academy. Nina tracked her down just north of the Mason Dixon line and choked her to death with a length of dental floss.

Nina assumed Lenore's identity at West Point, and was eventually recruited by the CIA. She excelled during training, mastering many weapons, but she favored sniper rifles and 9mm semi-automatic pistols. She became one of the best agents in the organization, and was the object of much jealousy and scorn. Driven by a selfish desire to see Nina fail, a rival agent started digging through Nina's past. Her secret was discovered, and a bounty was laid for her arrest. Rather than go to prison and back to a life of confined slavery, she went on the lam.

Over the years she has been tracked by some of the most ruthless and bloodthirsty agents, but she has snuffed them all out in her signature way - a single 9mm round, execution style. There are a number of theories as to how she ended up with the Double Crossers, but none of them are confirmed. Some say that Coco Bang Bang learned of Nina through her Navy SEAL father, and liked her style enough to recruit her. While it may never be clear how she came to join the ranks of these elite assassins, it is evident that she is armed and extremely dangerous.